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zymogen microparticle-tissue factor  (Sysmex Corporation)

 
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    Sysmex Corporation zymogen microparticle-tissue factor
    Anti-thrombin/Factor VIIa (AT/VIIa) complex, and <t>microparticle-TF</t> <t>(MP-TF)</t> levels in SARS-CoV-2 infection and controls. (A) AT/VIIa complex and (B) MP-TF plasma levels were determined by ELISA in healthy controls and patients with COVID-19 patients. Ixolaris, a TF inhibitor, blocks MP-associated TF activity. Each symbol correspond one patient. Shaded bars indicate the means, and the lines show the SEM. (C) Ixolaris prolongs the PT, but not the aPTT. (D) Thrombin generation assay. Reactions were initiated by the addition of CaCl 2 , phospholipids and TF, with and without Ixolaris, as indicated. Each curve shows the mean of triplicate reactions in pooled plasma. NS, non-significant; ** p < 0.01, **** p < 0.0001 (Kruskall-Wallis test).
    Zymogen Microparticle Tissue Factor, supplied by Sysmex Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/zymogen microparticle-tissue factor/product/Sysmex Corporation
    Average 90 stars, based on 1 article reviews
    zymogen microparticle-tissue factor - by Bioz Stars, 2026-05
    90/100 stars

    Images

    1) Product Images from "Upregulation of pulmonary tissue factor, loss of thrombomodulin and immunothrombosis in SARS-CoV-2 infection"

    Article Title: Upregulation of pulmonary tissue factor, loss of thrombomodulin and immunothrombosis in SARS-CoV-2 infection

    Journal: EClinicalMedicine

    doi: 10.1016/j.eclinm.2021.101069

    Anti-thrombin/Factor VIIa (AT/VIIa) complex, and microparticle-TF (MP-TF) levels in SARS-CoV-2 infection and controls. (A) AT/VIIa complex and (B) MP-TF plasma levels were determined by ELISA in healthy controls and patients with COVID-19 patients. Ixolaris, a TF inhibitor, blocks MP-associated TF activity. Each symbol correspond one patient. Shaded bars indicate the means, and the lines show the SEM. (C) Ixolaris prolongs the PT, but not the aPTT. (D) Thrombin generation assay. Reactions were initiated by the addition of CaCl 2 , phospholipids and TF, with and without Ixolaris, as indicated. Each curve shows the mean of triplicate reactions in pooled plasma. NS, non-significant; ** p < 0.01, **** p < 0.0001 (Kruskall-Wallis test).
    Figure Legend Snippet: Anti-thrombin/Factor VIIa (AT/VIIa) complex, and microparticle-TF (MP-TF) levels in SARS-CoV-2 infection and controls. (A) AT/VIIa complex and (B) MP-TF plasma levels were determined by ELISA in healthy controls and patients with COVID-19 patients. Ixolaris, a TF inhibitor, blocks MP-associated TF activity. Each symbol correspond one patient. Shaded bars indicate the means, and the lines show the SEM. (C) Ixolaris prolongs the PT, but not the aPTT. (D) Thrombin generation assay. Reactions were initiated by the addition of CaCl 2 , phospholipids and TF, with and without Ixolaris, as indicated. Each curve shows the mean of triplicate reactions in pooled plasma. NS, non-significant; ** p < 0.01, **** p < 0.0001 (Kruskall-Wallis test).

    Techniques Used: Infection, Enzyme-linked Immunosorbent Assay, Activity Assay



    Similar Products

    zymogen microparticle-tissue factor  (Sysmex Corporation)
    90
    Sysmex Corporation zymogen microparticle-tissue factor
    Anti-thrombin/Factor VIIa (AT/VIIa) complex, and <t>microparticle-TF</t> <t>(MP-TF)</t> levels in SARS-CoV-2 infection and controls. (A) AT/VIIa complex and (B) MP-TF plasma levels were determined by ELISA in healthy controls and patients with COVID-19 patients. Ixolaris, a TF inhibitor, blocks MP-associated TF activity. Each symbol correspond one patient. Shaded bars indicate the means, and the lines show the SEM. (C) Ixolaris prolongs the PT, but not the aPTT. (D) Thrombin generation assay. Reactions were initiated by the addition of CaCl 2 , phospholipids and TF, with and without Ixolaris, as indicated. Each curve shows the mean of triplicate reactions in pooled plasma. NS, non-significant; ** p < 0.01, **** p < 0.0001 (Kruskall-Wallis test).
    Zymogen Microparticle Tissue Factor, supplied by Sysmex Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/zymogen microparticle-tissue factor/product/Sysmex Corporation
    Average 90 stars, based on 1 article reviews
    zymogen microparticle-tissue factor - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Anti-thrombin/Factor VIIa (AT/VIIa) complex, and microparticle-TF (MP-TF) levels in SARS-CoV-2 infection and controls. (A) AT/VIIa complex and (B) MP-TF plasma levels were determined by ELISA in healthy controls and patients with COVID-19 patients. Ixolaris, a TF inhibitor, blocks MP-associated TF activity. Each symbol correspond one patient. Shaded bars indicate the means, and the lines show the SEM. (C) Ixolaris prolongs the PT, but not the aPTT. (D) Thrombin generation assay. Reactions were initiated by the addition of CaCl 2 , phospholipids and TF, with and without Ixolaris, as indicated. Each curve shows the mean of triplicate reactions in pooled plasma. NS, non-significant; ** p < 0.01, **** p < 0.0001 (Kruskall-Wallis test).

    Journal: EClinicalMedicine

    Article Title: Upregulation of pulmonary tissue factor, loss of thrombomodulin and immunothrombosis in SARS-CoV-2 infection

    doi: 10.1016/j.eclinm.2021.101069

    Figure Lengend Snippet: Anti-thrombin/Factor VIIa (AT/VIIa) complex, and microparticle-TF (MP-TF) levels in SARS-CoV-2 infection and controls. (A) AT/VIIa complex and (B) MP-TF plasma levels were determined by ELISA in healthy controls and patients with COVID-19 patients. Ixolaris, a TF inhibitor, blocks MP-associated TF activity. Each symbol correspond one patient. Shaded bars indicate the means, and the lines show the SEM. (C) Ixolaris prolongs the PT, but not the aPTT. (D) Thrombin generation assay. Reactions were initiated by the addition of CaCl 2 , phospholipids and TF, with and without Ixolaris, as indicated. Each curve shows the mean of triplicate reactions in pooled plasma. NS, non-significant; ** p < 0.01, **** p < 0.0001 (Kruskall-Wallis test).

    Article Snippet: Zymogen Microparticle-Tissue Factor (MP-TF) was purchased from Hyphen Biomed/Aniara Diagnostica (West Chester, OH).

    Techniques: Infection, Enzyme-linked Immunosorbent Assay, Activity Assay